Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase type 2' and Ligand = 'BDBM50145431'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase type 2 (Homo sapiens (Human))	BDBM50145431 (CHEMBL3764151) Show SMILES CC(C)C1=CC[C@H](Cn2cc(CNC(=O)OC(C)(C)C)nn2)[C@]11CCC(=O)C=C1 |r,c:29,t:3| Show InChI InChI=1S/C22H32N4O3/c1-15(2)19-7-6-16(22(19)10-8-18(27)9-11-22)13-26-14-17(24-25-26)12-23-20(28)29-21(3,4)5/h7-8,10,14-16H,6,9,11-13H2,1-5H3,(H,23,28)/t16-,22+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of full length human 11beta-HSD2 expressed in HEK293 cells using cortisone as substrate incubated for 2 hrs by HTRF assay in presence of N...				Eur J Med Chem 110: 126-32 (2016) Article DOI: 10.1016/j.ejmech.2016.01.027 BindingDB Entry DOI: 10.7270/Q28P62DG
					More data for this Ligand-Target Pair