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Found 1 hit Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase type 2' and Ligand = 'BDBM50267558'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
11-beta-hydroxysteroid dehydrogenase type 2


(Mus musculus (mouse))		BDBM50267558
PNG
(CHEMBL4065535)
Show SMILES [H][C@@]12[C@@H](CO)CC[C@@]1(C)[C@]1(C)CC[C@@]3([H])C(C)(C)[C@@H](O)CC[C@]3(C)[C@@]1([H])C[C@H]2O |r|
Show InChI InChI=1S/C23H40O3/c1-20(2)16-7-11-22(4)17(21(16,3)9-8-18(20)26)12-15(25)19-14(13-24)6-10-23(19,22)5/h14-19,24-26H,6-13H2,1-5H3/t14-,15-,16+,17-,18+,19+,21+,22-,23-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China.

Curated by ChEMBL


Assay Description
Inhibition of full-length mouse 11beta-HSD2 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 1 hr by scintillation prox...

Eur J Med Chem 135: 324-338 (2017)


Article DOI: 10.1016/j.ejmech.2017.04.059
BindingDB Entry DOI: 10.7270/Q2CF9SK2
More data for this
Ligand-Target Pair