Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '15-hydroxyprostaglandin dehydrogenase [NAD(+)]' and Ligand = 'BDBM118076'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human))	BDBM118076 (US8637558, 111) Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCC2CCC(CC2)OC=O)cc1 |w:7.8,t:1,(8.38,-.79,;7.61,.54,;8.52,1.79,;7.61,3.04,;8.38,4.37,;6.15,2.56,;6.15,1.02,;4.82,3.33,;3.48,2.56,;3.48,1.02,;2.15,.25,;.82,1.02,;-.52,.25,;-1.85,1.02,;-3.19,.25,;-4.52,1.02,;-5.85,.25,;-5.85,-1.29,;-4.52,-2.06,;-3.19,-1.29,;-7.19,-2.06,;-8.52,-1.29,;-9.85,-2.06,;.82,2.56,;2.15,3.33,)| Show InChI InChI=1S/C18H19NO5S/c20-11-24-15-7-3-13(4-8-15)10-23-14-5-1-12(2-6-14)9-16-17(21)19-18(22)25-16/h1-2,5-6,9,11,13,15H,3-4,7-8,10H2,(H,19,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9.33E+3	n/a	n/a	n/a	n/a	7.5	n/a
Industry-Academic Cooperation Foundation, Chosun University US Patent					Assay Description Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...				US Patent US8637558 (2014) BindingDB Entry DOI: 10.7270/Q280519F
					More data for this Ligand-Target Pair