Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '15-hydroxyprostaglandin dehydrogenase [NAD(+)]' and Ligand = 'BDBM50378623'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human))	BDBM50378623 (CHEMBL599004 | US8637558, 6) Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCc2ccccn2)cc1 |w:7.8,t:1| Show InChI InChI=1S/C17H14N2O3S/c20-16-15(23-17(21)19-16)11-12-4-6-14(7-5-12)22-10-8-13-3-1-2-9-18-13/h1-7,9,11H,8,10H2,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	592	n/a	n/a	n/a	n/a	7.5	n/a
Industry-Academic Cooperation Foundation, Chosun University US Patent					Assay Description Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...				US Patent US8637558 (2014) BindingDB Entry DOI: 10.7270/Q280519F
					More data for this Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human))	BDBM50378623 (CHEMBL599004 | US8637558, 6) Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCc2ccccn2)cc1 |w:7.8,t:1| Show InChI InChI=1S/C17H14N2O3S/c20-16-15(23-17(21)19-16)11-12-4-6-14(7-5-12)22-10-8-13-3-1-2-9-18-13/h1-7,9,11H,8,10H2,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Chosun University Curated by ChEMBL					Assay Description Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry				Bioorg Med Chem 18: 1428-33 (2010) Article DOI: 10.1016/j.bmc.2010.01.016 BindingDB Entry DOI: 10.7270/Q2Z0393H
					More data for this Ligand-Target Pair