Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '15-hydroxyprostaglandin dehydrogenase [NAD(+)]' and Ligand = 'BDBM50378627'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human))	BDBM50378627 (CHEMBL590988 | US8637558, 19) Show SMILES Cc1ncsc1CCOc1ccc(C=C2SC(O)=NC2=O)cc1 |w:13.13,c:18| Show InChI InChI=1S/C16H14N2O3S2/c1-10-13(22-9-17-10)6-7-21-12-4-2-11(3-5-12)8-14-15(19)18-16(20)23-14/h2-5,8-9H,6-7H2,1H3,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	636	n/a	n/a	n/a	n/a	n/a	n/a
Chosun University Curated by ChEMBL					Assay Description Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry				Bioorg Med Chem 18: 1428-33 (2010) Article DOI: 10.1016/j.bmc.2010.01.016 BindingDB Entry DOI: 10.7270/Q2Z0393H
					More data for this Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human))	BDBM50378627 (CHEMBL590988 | US8637558, 19) Show SMILES Cc1ncsc1CCOc1ccc(C=C2SC(O)=NC2=O)cc1 |w:13.13,c:18| Show InChI InChI=1S/C16H14N2O3S2/c1-10-13(22-9-17-10)6-7-21-12-4-2-11(3-5-12)8-14-15(19)18-16(20)23-14/h2-5,8-9H,6-7H2,1H3,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a	7.5	n/a
Industry-Academic Cooperation Foundation, Chosun University US Patent					Assay Description Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...				US Patent US8637558 (2014) BindingDB Entry DOI: 10.7270/Q280519F
					More data for this Ligand-Target Pair