Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '17-beta-hydroxysteroid dehydrogenase 14' and Ligand = 'BDBM50422417'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
17-beta-hydroxysteroid dehydrogenase 14 (Homo sapiens (Human))	BDBM50422417 (CHEMBL4165659) Show SMILES Oc1cc(ccc1F)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C46H84N6O2/c1-53-45-29-17-15-27-43(45)41-51-39-25-37-49-35-23-13-11-21-33-47-31-19-9-7-5-3-4-6-8-10-20-32-48-34-22-12-14-24-36-50-38-26-40-52-42-44-28-16-18-30-46(44)54-2/h15-18,27-30,47-52H,3-14,19-26,31-42H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Marburg Curated by ChEMBL					Assay Description Binding affinity to recombinant 17beta-HSD14 (unknown origin) expressed in Escherichia coli BL21 pLysS strain using E2 as substrate in presence of NA...				Eur J Med Chem 155: 61-76 (2018) Article DOI: 10.1016/j.ejmech.2018.05.029 BindingDB Entry DOI: 10.7270/Q23F4S76
					More data for this Ligand-Target Pair