Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '17-beta-hydroxysteroid dehydrogenase type 1' and Ligand = 'BDBM50331007'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human))	BDBM50331007 ((5-(4-hydroxy-3-methylphenyl)thiophen-3-yl)(3-hydr...) Show SMILES Cc1cc(ccc1O)-c1cc(cs1)C(=O)c1cccc(O)c1 Show InChI InChI=1S/C18H14O3S/c1-11-7-12(5-6-16(11)20)17-9-14(10-22-17)18(21)13-3-2-4-15(19)8-13/h2-10,19-20H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	199	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placenta 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 mins				J Med Chem 53: 8176-86 (2010) Article DOI: 10.1021/jm101073q BindingDB Entry DOI: 10.7270/Q2R49R0B
					More data for this Ligand-Target Pair