Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '17-beta-hydroxysteroid dehydrogenase type 2' and Ligand = 'BDBM50266402'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
17-beta-hydroxysteroid dehydrogenase type 2 (Homo sapiens (Human))	BDBM50266402 (CHEMBL4071245) Show SMILES NS(=O)(=O)Oc1ccc(cc1Cl)-c1ccc(s1)C(=O)c1c(F)ccc(O)c1F Show InChI InChI=1S/C17H10ClF2NO5S2/c18-9-7-8(1-4-12(9)26-28(21,24)25)13-5-6-14(27-13)17(23)15-10(19)2-3-11(22)16(15)20/h1-7,22H,(H2,21,24,25)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental cytosolic 17beta-HSD2 using [3H]-E2/E2 substrate and NAD+ after 20 mins by HPLC based radio-detection method				J Med Chem 60: 4086-4092 (2017) Article DOI: 10.1021/acs.jmedchem.7b00062 BindingDB Entry DOI: 10.7270/Q2J968VG
					More data for this Ligand-Target Pair