Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial' and Ligand = 'BDBM50023352'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial (Mus musculus)	BDBM50023352 (CHEMBL3329773) Show SMILES COc1cc(OC)cc(\C=C\c2ccc(CCC(=O)C(C)(C)C)cc2)c1 Show InChI InChI=1S/C23H28O3/c1-23(2,3)22(24)13-12-18-8-6-17(7-9-18)10-11-19-14-20(25-4)16-21(15-19)26-5/h6-11,14-16H,12-13H2,1-5H3/b11-10+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of mouse CYP27B1 using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reductase and NADPH incubated at 37 degC for 2...				J Med Chem 57: 7702-15 (2014) Article DOI: 10.1021/jm5009314 BindingDB Entry DOI: 10.7270/Q2DN46ND
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