Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '26S proteasome non-ATPase regulatory subunit 14' and Ligand = 'BDBM401031'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
26S proteasome non-ATPase regulatory subunit 14 (Homo sapiens (Human))	BDBM401031 (US10005735, Compound 29) Show SMILES Cc1nc(CCNC(=O)c2cnc3c(S)cccc3c2)sc1C(O)=O Show InChI InChI=1S/C17H15N3O3S2/c1-9-15(17(22)23)25-13(20-9)5-6-18-16(21)11-7-10-3-2-4-12(24)14(10)19-8-11/h2-4,7-8,24H,5-6H2,1H3,(H,18,21)(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...				Bioorg Med Chem 17: 8086-92 (2009) BindingDB Entry DOI: 10.7270/Q22R3V09
					More data for this Ligand-Target Pair