Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM50007301 (CHEMBL102199 | Sodium; 6-{3-[bis-(4-fluoro-phenyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoechst AG Curated by ChEMBL | Assay Description In vitro inhibition of HMG-CoA reductase in solubilized rat liver. | J Med Chem 34: 2962-83 (1991) BindingDB Entry DOI: 10.7270/Q2C829WX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human)) | BDBM50007301 (CHEMBL102199 | Sodium; 6-{3-[bis-(4-fluoro-phenyl)...) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoechst AG Curated by ChEMBL | Assay Description Inhibition of the incorporation of sodium [14C]acetate into cholesterol in HEP G2 cells. | J Med Chem 34: 2962-83 (1991) BindingDB Entry DOI: 10.7270/Q2C829WX | |||||||||||
More data for this Ligand-Target Pair |