Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ' and Ligand = 'BDBM31964'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31964 (carbohydrazide derivative, 5g) Show SMILES Oc1c(Br)cc(C=NNC(=O)c2ccc3ccccc3c2O)c(O)c1Br |w:6.5| Show InChI InChI=1S/C18H12Br2N2O4/c19-13-7-10(15(23)14(20)17(13)25)8-21-22-18(26)12-6-5-9-3-1-2-4-11(9)16(12)24/h1-8,23-25H,(H,22,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
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