BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '3-oxo-5-alpha-steroid 4-dehydrogenase 1' and Ligand = 'BDBM50034157'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
3-oxo-5-alpha-steroid 4-dehydrogenase 1


(Homo sapiens (Human))		BDBM50034157
PNG
(CHEMBL276320 | N-Phenyl-N-((4aR,6aS,7S,11aR)-1,4a,...)
Show SMILES CN1[C@@H]2CCC3C4CC[C@H](N(C(=O)c5ccccc5)c5ccccc5)[C@@]4(C)CCC3[C@@]2(C)CCC1=O
Show InChI InChI=1S/C32H40N2O2/c1-31-21-19-29(35)33(3)27(31)16-14-24-25-15-17-28(32(25,2)20-18-26(24)31)34(23-12-8-5-9-13-23)30(36)22-10-6-4-7-11-22/h4-13,24-28H,14-21H2,1-3H3/t24?,25?,26?,27-,28+,31-,32+/m1/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 2.90n/an/an/an/an/an/a



CHUL Research Center

Curated by ChEMBL


Assay Description
In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cells

J Med Chem 38: 1158-73 (1995)


BindingDB Entry DOI: 10.7270/Q2NG4R90
More data for this
Ligand-Target Pair