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Found 1 hit Enz. Inhib. hit(s) with Target = '3-oxo-5-alpha-steroid 4-dehydrogenase 1' and Ligand = 'BDBM50055147'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
3-oxo-5-alpha-steroid 4-dehydrogenase 1


(Rattus norvegicus)		BDBM50055147
PNG
(4-{2-[(E)-3-(1-Benzhydryl-1H-indol-5-yl)-pent-2-en...)
Show SMILES CC\C(=C/C(=O)Nc1ccccc1OCCCC(O)=O)c1ccc2n(ccc2c1)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C36H34N2O4/c1-2-26(25-34(39)37-31-16-9-10-17-33(31)42-23-11-18-35(40)41)29-19-20-32-30(24-29)21-22-38(32)36(27-12-5-3-6-13-27)28-14-7-4-8-15-28/h3-10,12-17,19-22,24-25,36H,2,11,18,23H2,1H3,(H,37,39)(H,40,41)/b26-25+
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n/an/a 2.50E+3n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
5 alpha- reductase inhibitory activity

J Med Chem 39: 5047-52 (1997)


Article DOI: 10.1021/jm9601819
BindingDB Entry DOI: 10.7270/Q2TQ6263
More data for this
Ligand-Target Pair