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Found 1 hit Enz. Inhib. hit(s) with Target = '3-oxo-5-alpha-steroid 4-dehydrogenase 1' and Ligand = 'BDBM50289143'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
3-oxo-5-alpha-steroid 4-dehydrogenase 1


(Rattus norvegicus)		BDBM50289143
PNG
((5R,10R,14S)-17-(2-Hydroxy-1-methyl-ethyl)-10-meth...)
Show SMILES [H][C@@]12CC[C@H](C(C)CO)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])C(=[N+]=[N-])C(=O)CC[C@]12C
Show InChI InChI=1S/C22H34N2O2/c1-13(12-25)15-6-7-16-14-4-5-18-20(24-23)19(26)9-11-22(18,3)17(14)8-10-21(15,16)2/h13-18,25H,4-12H2,1-3H3/t13?,14-,15+,16-,17-,18-,21+,22+/m0/s1
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PC cid
PC sid
UniChem
Article
 35n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Apparent inhibitory activity of the compound was determined against rat prostatic Steroid 5-alpha-reductase type I

Bioorg Med Chem Lett 6: 883-884 (1996)


Article DOI: 10.1016/0960-894X(96)00136-9
BindingDB Entry DOI: 10.7270/Q24B319W
More data for this
Ligand-Target Pair