BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = '3-oxoacyl-[acyl-carrier-protein] synthase 2' and Ligand = 'BDBM50241313'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
3-oxoacyl-[acyl-carrier-protein] synthase 2 (Mycobacterium tuberculosis)	BDBM50241313 ((5R)-4-hydroxy-3,5-dimethyl-5-[(1E)-2-methylbuta-1...) Show SMILES CC1C(=O)S[C@](C)(\C=C(/C)C=C)C1=O \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Allergy and Infectious Diseases Curated by ChEMBL					Assay Description Inhibitory activity against KasB from Mycobacterium tuberculosis H37Rv				J Med Chem 49: 159-71 (2006) Article DOI: 10.1021/jm050825p BindingDB Entry DOI: 10.7270/Q2NG4RDB
					More data for this Ligand-Target Pair
3-oxoacyl-[acyl-carrier-protein] synthase 2 (Staphylococcus aureus)	BDBM50241313 ((5R)-4-hydroxy-3,5-dimethyl-5-[(1E)-2-methylbuta-1...) Show SMILES CC1C(=O)S[C@](C)(\C=C(/C)C=C)C1=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.07E+5	n/a	n/a	n/a	n/a	n/a
Colorado State University Curated by ChEMBL					Assay Description Binding affinity to Staphylococcus aureus wild type FabF expressed in Escherichia coli BL21 (DE3) PlysS cells by intrinsic tryptophan fluorescence qu...				J Med Chem 59: 5377-90 (2016) Article DOI: 10.1021/acs.jmedchem.6b00236 BindingDB Entry DOI: 10.7270/Q2CR5XVW
Colorado State University Curated by ChEMBL					More data for this Ligand-Target Pair
3-oxoacyl-[acyl-carrier-protein] synthase 2 (Staphylococcus aureus)	BDBM50241313 ((5R)-4-hydroxy-3,5-dimethyl-5-[(1E)-2-methylbuta-1...) Show SMILES CC1C(=O)S[C@](C)(\C=C(/C)C=C)C1=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	8.80E+4	n/a	n/a	n/a	n/a	n/a
Colorado State University Curated by ChEMBL					Assay Description Binding affinity to Staphylococcus aureus FabF C165Q mutant expressed in Escherichia coli BL21 (DE3) PlysS cells by intrinsic tryptophan fluorescence...				J Med Chem 59: 5377-90 (2016) Article DOI: 10.1021/acs.jmedchem.6b00236 BindingDB Entry DOI: 10.7270/Q2CR5XVW
Colorado State University Curated by ChEMBL					More data for this Ligand-Target Pair
3-oxoacyl-[acyl-carrier-protein] synthase 2 (Staphylococcus aureus)	BDBM50241313 ((5R)-4-hydroxy-3,5-dimethyl-5-[(1E)-2-methylbuta-1...) Show SMILES CC1C(=O)S[C@](C)(\C=C(/C)C=C)C1=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	8.80E+4	n/a	n/a	n/a	n/a	n/a
Colorado State University Curated by ChEMBL					Assay Description Binding affinity to Staphylococcus aureus FabF C165Q mutant expressed in Escherichia coli BL21 (DE3) PlysS cells by intrinsic tryptophan fluorescence...				J Med Chem 59: 5377-90 (2016) Article DOI: 10.1021/acs.jmedchem.6b00236 BindingDB Entry DOI: 10.7270/Q2CR5XVW
Colorado State University Curated by ChEMBL					More data for this Ligand-Target Pair
3-oxoacyl-[acyl-carrier-protein] synthase 2 (Staphylococcus aureus)	BDBM50241313 ((5R)-4-hydroxy-3,5-dimethyl-5-[(1E)-2-methylbuta-1...) Show SMILES CC1C(=O)S[C@](C)(\C=C(/C)C=C)C1=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.07E+5	n/a	n/a	n/a	n/a	n/a
Colorado State University Curated by ChEMBL					Assay Description Binding affinity to Staphylococcus aureus wild type FabF expressed in Escherichia coli BL21 (DE3) PlysS cells by intrinsic tryptophan fluorescence qu...				J Med Chem 59: 5377-90 (2016) Article DOI: 10.1021/acs.jmedchem.6b00236 BindingDB Entry DOI: 10.7270/Q2CR5XVW
Colorado State University Curated by ChEMBL					More data for this Ligand-Target Pair