Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '3-phosphoinositide-dependent protein kinase 1' and Ligand = 'BDBM50296953'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50296953 ((Z)-5-(2,4-Dichlorophenyl)-3-phenylpent-2-enoic Ac...) Show SMILES OC(=O)\C=C(\CCc1ccc(Cl)cc1Cl)c1ccccc1 Show InChI InChI=1S/C17H14Cl2O2/c18-15-9-8-13(16(19)11-15)6-7-14(10-17(20)21)12-4-2-1-3-5-12/h1-5,8-11H,6-7H2,(H,20,21)/b14-10-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Binding affinity to PDK1 (50 to 359) by isothermal titration calorimetry				J Med Chem 52: 4683-93 (2009) Article DOI: 10.1021/jm9001499 BindingDB Entry DOI: 10.7270/Q2FB52ZC
					More data for this Ligand-Target Pair