Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '3-phosphoinositide-dependent protein kinase 1 [51-359]' and Ligand = 'BDBM282422'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-phosphoinositide-dependent protein kinase 1 [51-359] (Homo sapiens (Human))	BDBM282422 (2-(4-(3-amino-1H-pyrazolo [3,4-b]pyridin-5-yl) ben...) Show SMILES Nc1n[nH]c2ncc(cc12)-c1ccc(CNc2ncc(cc2C(=O)NC2CCCC2)C(F)(F)F)cc1 Show InChI InChI=1S/C25H24F3N7O/c26-25(27,28)17-10-20(24(36)33-18-3-1-2-4-18)22(32-13-17)30-11-14-5-7-15(8-6-14)16-9-19-21(29)34-35-23(19)31-12-16/h5-10,12-13,18H,1-4,11H2,(H,30,32)(H,33,36)(H3,29,31,34,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals, Inc.; Millenium Pharmaceuticals, Inc. US Patent					Assay Description PDK1 (amino acids 51-359) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) were expressed as N-terminally tagged GST fusi...				US Patent US10030016 (2018) BindingDB Entry DOI: 10.7270/Q2S46V16
					More data for this Ligand-Target Pair