Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '3-phosphoinositide-dependent protein kinase 1 [51-360]' and Ligand = 'BDBM366190'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-phosphoinositide-dependent protein kinase 1 [51-360] (Homo sapiens (Human))	BDBM366190 (US9873693, Compound 113 | US9873693, Compound 274) Show SMILES Fc1ccc(Cn2cccc(C(=O)NCCOc3ccc4[nH]c(=O)[nH]c4c3)c2=O)cc1F Show InChI InChI=1S/C22H18F2N4O4/c23-16-5-3-13(10-17(16)24)12-28-8-1-2-15(21(28)30)20(29)25-7-9-32-14-4-6-18-19(11-14)27-22(31)26-18/h1-6,8,10-11H,7,9,12H2,(H,25,29)(H2,26,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University					Assay Description A PDK1 kinase assay was performed as follows. PDK1 (amino acids 51-360) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) ...				J Med Chem 51: 68-76 (2008) BindingDB Entry DOI: 10.7270/Q2H41TRT
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 [51-360] (Homo sapiens (Human))	BDBM366190 (US9873693, Compound 113 | US9873693, Compound 274) Show SMILES Fc1ccc(Cn2cccc(C(=O)NCCOc3ccc4[nH]c(=O)[nH]c4c3)c2=O)cc1F Show InChI InChI=1S/C22H18F2N4O4/c23-16-5-3-13(10-17(16)24)12-28-8-1-2-15(21(28)30)20(29)25-7-9-32-14-4-6-18-19(11-14)27-22(31)26-18/h1-6,8,10-11H,7,9,12H2,(H,25,29)(H2,26,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University					Assay Description A PDK1 kinase assay was performed as follows. PDK1 (amino acids 51-360) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) ...				J Med Chem 51: 68-76 (2008) BindingDB Entry DOI: 10.7270/Q2H41TRT
					More data for this Ligand-Target Pair