Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3-phosphoshikimate 1-carboxyvinyltransferase (Escherichia coli (strain K12)) | BDBM50280242 ((3R,4S,5R)-4,5-Dihydroxy-3-phosphonooxy-cyclohex-1...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article | n/a | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description The compound was tested for the inhibition of E. coli 5-enolpyruvyl-shikimate-3-phosphate synthase (EPSP). | Bioorg Med Chem Lett 3: 2857-2862 (1993) Article DOI: 10.1016/S0960-894X(01)80779-4 BindingDB Entry DOI: 10.7270/Q2SX6D43 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
3-phosphoshikimate 1-carboxyvinyltransferase (Escherichia coli (strain K12)) | BDBM50280242 ((3R,4S,5R)-4,5-Dihydroxy-3-phosphonooxy-cyclohex-1...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article | n/a | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Escherichia coli EPSP synthase | Bioorg Med Chem Lett 4: 2605-2608 (1994) Article DOI: 10.1016/S0960-894X(01)80293-6 BindingDB Entry DOI: 10.7270/Q25M666T | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
3-phosphoshikimate 1-carboxyvinyltransferase (Escherichia coli (strain K12)) | BDBM50280242 ((3R,4S,5R)-4,5-Dihydroxy-3-phosphonooxy-cyclohex-1...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article | n/a | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Dissociation constant of the at EPSP synthase was determined | Bioorg Med Chem Lett 2: 1435-1440 (1992) Article DOI: 10.1016/S0960-894X(00)80527-2 BindingDB Entry DOI: 10.7270/Q2XD1244 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
3-phosphoshikimate 1-carboxyvinyltransferase (Escherichia coli (strain K12)) | BDBM50280242 ((3R,4S,5R)-4,5-Dihydroxy-3-phosphonooxy-cyclohex-1...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article | n/a | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against EPSP(5-enolpyruvylshikimate 3-phosphate) synthase in Escherichia coli. | Bioorg Med Chem Lett 6: 2853-2858 (1996) Article DOI: 10.1016/S0960-894X(96)00527-6 BindingDB Entry DOI: 10.7270/Q2833SJZ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |