Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '4-hydroxyphenylpyruvate dioxygenase' and Ligand = 'BDBM50024723'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50024723 (CHEMBL3342601) Show SMILES COc1ccccc1-n1c(C)nc2ccc(cc2c1=O)C(=O)c1cnn(C)c1O |(24.63,-14.14,;23.28,-13.4,;23.25,-11.86,;24.57,-11.06,;24.54,-9.52,;23.18,-8.78,;21.87,-9.58,;21.91,-11.12,;20.59,-11.92,;20.63,-13.47,;21.98,-14.21,;19.3,-14.27,;17.95,-13.53,;16.63,-14.32,;15.28,-13.58,;15.25,-12.03,;16.56,-11.24,;17.91,-11.98,;19.23,-11.17,;19.19,-9.63,;13.91,-11.29,;13.87,-9.75,;12.59,-12.09,;12.46,-13.62,;10.96,-13.97,;10.16,-12.66,;8.63,-12.53,;11.16,-11.49,;10.81,-9.99,)| Show InChI InChI=1S/C21H18N4O4/c1-12-23-16-9-8-13(19(26)15-11-22-24(2)20(15)27)10-14(16)21(28)25(12)17-6-4-5-7-18(17)29-3/h4-11,27H,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of purified His6-tagged recombinant human HPPD assessed as inhibition of maleylacetoacetate formation after 30 mins by UV/visible spectrop...				Bioorg Med Chem 22: 5194-211 (2014) Article DOI: 10.1016/j.bmc.2014.08.011 BindingDB Entry DOI: 10.7270/Q2DF6SRG
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