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Found 1 hit Enz. Inhib. hit(s) with Target = '4-hydroxyphenylpyruvate dioxygenase' and Ligand = 'BDBM50024741'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
4-hydroxyphenylpyruvate dioxygenase


(Homo sapiens (Human))		BDBM50024741
PNG
(CHEMBL3342418)
Show SMILES Cc1nn(C)c(O)c1C(=O)c1ccc2nc(C)n(-c3cccc(Br)c3)c(=O)c2c1
Show InChI InChI=1S/C21H17BrN4O3/c1-11-18(21(29)25(3)24-11)19(27)13-7-8-17-16(9-13)20(28)26(12(2)23-17)15-6-4-5-14(22)10-15/h4-10,29H,1-3H3
PDB

KEGG

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PC cid
PC sid
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Similars
Article
PubMed
 93n/an/an/an/an/an/an/an/a



Central China Normal University

Curated by ChEMBL


Assay Description
Inhibition of purified His6-tagged recombinant human HPPD assessed as inhibition of maleylacetoacetate formation after 30 mins by UV/visible spectrop...

Bioorg Med Chem 22: 5194-211 (2014)


Article DOI: 10.1016/j.bmc.2014.08.011
BindingDB Entry DOI: 10.7270/Q2DF6SRG
More data for this
Ligand-Target Pair