Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '4-hydroxyphenylpyruvate dioxygenase' and Ligand = 'BDBM50536951'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536951 (CHEMBL4564075) Show SMILES CC1CC(O)=C(C(=O)c2cccc(OCc3ccc(C)cc3)c2[N+]([O-])=O)C(=O)C1 |t:4| Show InChI InChI=1S/C22H21NO6/c1-13-6-8-15(9-7-13)12-29-19-5-3-4-16(21(19)23(27)28)22(26)20-17(24)10-14(2)11-18(20)25/h3-9,14,24H,10-12H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	168	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
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