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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5'-AMP-activated protein kinase catalytic subunit alpha-2/subunit beta-1/subunit gamma-1' and Ligand = 'BDBM50246153'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5'-AMP-activated protein kinase catalytic subunit alpha-2/subunit beta-1/subunit gamma-1


(Homo sapiens (Human))		BDBM50246153
PNG
(CHEMBL4071158)
Show SMILES OC(=O)c1cccc(Sc2nc3cc(c(Cl)cc3[nH]2)-c2ccc(cc2)-c2ccccc2O)c1
Show InChI InChI=1S/C26H17ClN2O3S/c27-21-14-23-22(28-26(29-23)33-18-5-3-4-17(12-18)25(31)32)13-20(21)16-10-8-15(9-11-16)19-6-1-2-7-24(19)30/h1-14,30H,(H,28,29)(H,31,32)
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PC cid
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Similars
Article
PubMed
n/an/an/an/a 29n/an/an/an/a



Metabasis Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant phosphorylated AMPK complex 7 alpha2/beta1/gamma1 expressed in baculovirus infected Sf21 cells assessed as phos...

J Med Chem 60: 9040-9052 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01344
BindingDB Entry DOI: 10.7270/Q2V69N0Q
More data for this
Ligand-Target Pair