Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5'-nucleotidase (Homo sapiens (Human)) | BDBM50561892 (CHEMBL4795486) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human C-terminal His-tagged CD73 (27 to 549 residues) expressed in Sf9 cells using [2,8-3H]-AMP as substrate incubated for ... | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00391 BindingDB Entry DOI: 10.7270/Q2CF9TTM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50561892 (CHEMBL4795486) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of CD73 in human MDA-MB-231 cells using [2,8-3H]-AMP as substrate incubated for 25 mins by scintillation counting method | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00391 BindingDB Entry DOI: 10.7270/Q2CF9TTM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Rattus norvegicus (Rat)) | BDBM50561892 (CHEMBL4795486) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant rat CD73 expressed in Sf9 cells using [2,8-3H]-AMP as substrate incubated for 25 mins by scintillation counting method | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00391 BindingDB Entry DOI: 10.7270/Q2CF9TTM | |||||||||||
More data for this Ligand-Target Pair |