Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1A' and Ligand = 'BDBM264097'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM264097 (1-(4-(4-(4-(5-fluoro-1H-indol-3-yl)butyl)piperazin...) Show SMILES Fc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(cc3)-n3ccccc3=O)c2c1 Show InChI InChI=1S/C27H29FN4O/c28-22-7-12-26-25(19-22)21(20-29-26)5-1-3-13-30-15-17-31(18-16-30)23-8-10-24(11-9-23)32-14-4-2-6-27(32)33/h2,4,6-12,14,19-20,29H,1,3,5,13,15-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.190	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...				US Patent US9714232 (2017) BindingDB Entry DOI: 10.7270/Q28054N5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM264097 (1-(4-(4-(4-(5-fluoro-1H-indol-3-yl)butyl)piperazin...) Show SMILES Fc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(cc3)-n3ccccc3=O)c2c1 Show InChI InChI=1S/C27H29FN4O/c28-22-7-12-26-25(19-22)21(20-29-26)5-1-3-13-30-15-17-31(18-16-30)23-8-10-24(11-9-23)32-14-4-2-6-27(32)33/h2,4,6-12,14,19-20,29H,1,3,5,13,15-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	7.4	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...				US Patent US9714232 (2017) BindingDB Entry DOI: 10.7270/Q28054N5
					More data for this Ligand-Target Pair