Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50033437 (CHEMBL905 | MK 462 free base | N,N-dimethyl-2-[5-(...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1A receptor | J Med Chem 42: 526-31 (1999) Article DOI: 10.1021/jm9805945 BindingDB Entry DOI: 10.7270/Q2668CBM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50033437 (CHEMBL905 | MK 462 free base | N,N-dimethyl-2-[5-(...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | PubMed | 293 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre Fabre Curated by ChEMBL | Assay Description Binding affinity for cloned human 5-hydroxytryptamine 1A receptor | J Med Chem 38: 3602-7 (1995) BindingDB Entry DOI: 10.7270/Q25M66C2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50033437 (CHEMBL905 | MK 462 free base | N,N-dimethyl-2-[5-(...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL | Assay Description Binding activity against 5-hydroxytryptamine 1A receptor from pig cortex membrane using [3H]8-OH-DPAT-HT as radioligand. | J Med Chem 38: 1799-810 (1995) BindingDB Entry DOI: 10.7270/Q20V8DZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50033437 (CHEMBL905 | MK 462 free base | N,N-dimethyl-2-[5-(...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Compound was tested for its ability to displace [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in pig cortex | Citation and Details BindingDB Entry DOI: 10.7270/Q2SX6GDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50033437 (CHEMBL905 | MK 462 free base | N,N-dimethyl-2-[5-(...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 398 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL | Assay Description Binding activity against 5-hydroxytryptamine 3 receptor from rat cortex homogenate using [3H]-Q-ICS 205-930 as radioligand. | J Med Chem 38: 1799-810 (1995) BindingDB Entry DOI: 10.7270/Q20V8DZS | |||||||||||
More data for this Ligand-Target Pair |