Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2A' and Ligand = 'BDBM269506'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM269506 ((4-(2-chlorophenethyl)piperazin-1- yl)(imidazo[1,2...) Show SMILES Clc1ccccc1CCN1CCN(CC1)C(=O)c1cccn2ccnc12 Show InChI InChI=1S/C20H21ClN4O/c21-18-6-2-1-4-16(18)7-10-23-12-14-25(15-13-23)20(26)17-5-3-9-24-11-8-22-19(17)24/h1-6,8-9,11H,7,10,12-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.4	25
Arena Pharmaceuticals, Inc. US Patent					Assay Description Radioligand binding assays for human 5-HT2A serotonin receptor were conducted using the 5-HT2 agonist [125I]DOI as radioligand. To define nonspecific...				US Patent US10058549 (2018) BindingDB Entry DOI: 10.7270/Q2BK1FC8
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM269506 ((4-(2-chlorophenethyl)piperazin-1- yl)(imidazo[1,2...) Show SMILES Clc1ccccc1CCN1CCN(CC1)C(=O)c1cccn2ccnc12 Show InChI InChI=1S/C20H21ClN4O/c21-18-6-2-1-4-16(18)7-10-23-12-14-25(15-13-23)20(26)17-5-3-9-24-11-8-22-19(17)24/h1-6,8-9,11H,7,10,12-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University Curated by ChEMBL					Assay Description Modulator activity at 5-HT2A receptor (unknown origin)				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111569 BindingDB Entry DOI: 10.7270/Q2H41VXG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM269506 ((4-(2-chlorophenethyl)piperazin-1- yl)(imidazo[1,2...) Show SMILES Clc1ccccc1CCN1CCN(CC1)C(=O)c1cccn2ccnc12 Show InChI InChI=1S/C20H21ClN4O/c21-18-6-2-1-4-16(18)7-10-23-12-14-25(15-13-23)20(26)17-5-3-9-24-11-8-22-19(17)24/h1-6,8-9,11H,7,10,12-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University Curated by ChEMBL					Assay Description Modulator activity at 5-HT2A receptor (unknown origin)				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111569 BindingDB Entry DOI: 10.7270/Q2H41VXG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM269506 ((4-(2-chlorophenethyl)piperazin-1- yl)(imidazo[1,2...) Show SMILES Clc1ccccc1CCN1CCN(CC1)C(=O)c1cccn2ccnc12 Show InChI InChI=1S/C20H21ClN4O/c21-18-6-2-1-4-16(18)7-10-23-12-14-25(15-13-23)20(26)17-5-3-9-24-11-8-22-19(17)24/h1-6,8-9,11H,7,10,12-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.4	25
Arena Pharmaceuticals, Inc. US Patent					Assay Description Radioligand binding assays for human 5-HT2A serotonin receptor were conducted using the 5-HT2 agonist [125I]DOI as radioligand. To define nonspecific...				US Patent US9567327 (2017) BindingDB Entry DOI: 10.7270/Q2639RSB
					More data for this Ligand-Target Pair