Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50081701 (3-[2-(dimethylamino)ethyl]-1H-indol-4-ol | 4-hydro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2S46WX8 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (BOVINE) | BDBM50081701 (3-[2-(dimethylamino)ethyl]-1H-indol-4-ol | 4-hydro...) | PDB Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars | PubMed | 450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Stanford University Curated by PDSP Ki Database | J Neurosci 9: 3482-90 (1989) BindingDB Entry DOI: 10.7270/Q2FX77Z2 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50081701 (3-[2-(dimethylamino)ethyl]-1H-indol-4-ol | 4-hydro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of human 5HT2B expressed in HEK293T cells co-transfected with Galphaq-RLuc8, Ggamma1-GFP2 and Gbeta1 assessed as dissociation of Galphaq f... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00578 BindingDB Entry DOI: 10.7270/Q2BR8X3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50081701 (3-[2-(dimethylamino)ethyl]-1H-indol-4-ol | 4-hydro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 58 | n/a | n/a | n/a | n/a |
Organix Inc. Curated by ChEMBL | Assay Description Effective concentration required for accumulation of [3H]-inositol phosphate in cells transiently expressing human 5-hydroxytryptamine 2B receptor de... | Bioorg Med Chem Lett 15: 4555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.104 BindingDB Entry DOI: 10.7270/Q2PZ58B5 | |||||||||||
More data for this Ligand-Target Pair |