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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2B' and Ligand = 'BDBM50531775'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50531775
PNG
(CHEMBL4460604)
Show SMILES [O-][N+](=O)c1cn(cn1)-c1ccc(cc1)C(=O)C1CC1
Show InChI InChI=1S/C13H11N3O3/c17-13(9-1-2-9)10-3-5-11(6-4-10)15-7-12(14-8-15)16(18)19/h3-9H,1-2H2
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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.30n/an/an/an/a



CSIR-Central Drug Research Institute (CSIR-CDRI)

Curated by ChEMBL


Assay Description
Positive allosteric modulation of 5HT2B receptor (unknown origin) expressed in HEK293 cells co-expressing NFAT-RE assessed as increase in serotonin-i...

Eur J Med Chem 164: 499-516 (2019)


Article DOI: 10.1016/j.ejmech.2018.12.070
BindingDB Entry DOI: 10.7270/Q2XS5ZW2
More data for this
Ligand-Target Pair