Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50171264 (CHEMBL197646 | US11427604, Compound (I-43) | US115...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 82 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc. Curated by ChEMBL | Assay Description Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss... | Bioorg Med Chem Lett 15: 4555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.104 BindingDB Entry DOI: 10.7270/Q2PZ58B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50171264 (CHEMBL197646 | US11427604, Compound (I-43) | US115...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 84 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc. Curated by ChEMBL | Assay Description Inhibition constant against human 5-hydroxytryptamine 2C receptor [VGI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss... | Bioorg Med Chem Lett 15: 4555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.104 BindingDB Entry DOI: 10.7270/Q2PZ58B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat)) | BDBM50171264 (CHEMBL197646 | US11427604, Compound (I-43) | US115...) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 359 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc. Curated by ChEMBL | Assay Description Inhibition constant against rat 5-hydroxytryptamine 2C receptor using [3H]-mesulergine as radioligand with the compound (10 uM) dissolved in DMSO | Bioorg Med Chem Lett 15: 4555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.104 BindingDB Entry DOI: 10.7270/Q2PZ58B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50171264 (CHEMBL197646 | US11427604, Compound (I-43) | US115...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 99 | n/a | n/a | n/a | n/a |
Organix Inc. Curated by ChEMBL | Assay Description Effective concentration required for accumulation of [3H]-inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2C receptor determi... | Bioorg Med Chem Lett 15: 4555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.104 BindingDB Entry DOI: 10.7270/Q2PZ58B5 | |||||||||||
More data for this Ligand-Target Pair |