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Found 1 hit Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2C' and Ligand = 'BDBM50476466'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50476466
PNG
(CHEMBL397709)
Show SMILES COc1ccc(cc1OCCN1[C@@H](C)CCC[C@H]1C)N1Cc2cc(Cl)cc(Cl)c2C1=O
Show InChI InChI=1S/C24H28Cl2N2O3/c1-15-5-4-6-16(2)27(15)9-10-31-22-13-19(7-8-21(22)30-3)28-14-17-11-18(25)12-20(26)23(17)24(28)29/h7-8,11-13,15-16H,4-6,9-10,14H2,1-3H3/t15-,16+
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Article
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 6.30n/an/an/an/an/an/an/an/a



GlaxoSmithKline Medicine Research Centre

Curated by ChEMBL


Assay Description
Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells

Bioorg Med Chem Lett 17: 428-33 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.029
BindingDB Entry DOI: 10.7270/Q2TX3J4X
More data for this
Ligand-Target Pair