Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT) | BDBM50005835 ((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical College of Virginia/Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity of the compound was measured on 5-hydroxytryptamine 3 receptor in NG-108 cells labeled with [3H]-GR-65,630 | J Med Chem 37: 2828-30 (1994) BindingDB Entry DOI: 10.7270/Q2GH9H0R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT) | BDBM50005835 ((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Compound was tested for its ability to displace [3H]-Q-ICS 205-930 from 5-hydroxytryptamine 3 receptor in rat cortex homogenates | Citation and Details BindingDB Entry DOI: 10.7270/Q2SX6GDH | |||||||||||
More data for this Ligand-Target Pair |