Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 3A (Homo sapiens (Human)) | BDBM50293279 (1-Methyl-5-[(1-propylpiperidin-4-yl)methyloxy]-pyr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.92 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Caen Curated by ChEMBL | Assay Description Displacement of [3H]granisetron from human recombinant 5HT3 receptor | Bioorg Med Chem 17: 2607-22 (2009) Article DOI: 10.1016/j.bmc.2008.11.045 BindingDB Entry DOI: 10.7270/Q2CJ8DCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 3A (Homo sapiens (Human)) | BDBM50293279 (1-Methyl-5-[(1-propylpiperidin-4-yl)methyloxy]-pyr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 385 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Caen Curated by ChEMBL | Assay Description Antagonist activity at 5HT3 receptor in hybrid NG108-15 cells assessed as inhibition of 5HT-induced current by electrophysiology | Bioorg Med Chem 17: 2607-22 (2009) Article DOI: 10.1016/j.bmc.2008.11.045 BindingDB Entry DOI: 10.7270/Q2CJ8DCG | |||||||||||
More data for this Ligand-Target Pair |