Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 4 (GUINEA PIG) | BDBM50056415 (2-piperidinopropyl 4-amino-5-chloro-2-methoxybenzo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 3.98 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Bioscience Curated by PDSP Ki Database | FASEB J 10: 1398-407 (1996) Article DOI: 10.1096/fasebj.10.12.8903510 BindingDB Entry DOI: 10.7270/Q2TQ602G | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 4 (GUINEA PIG) | BDBM50056415 (2-piperidinopropyl 4-amino-5-chloro-2-methoxybenzo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena Curated by ChEMBL | Assay Description Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 mins | Eur J Med Chem 82: 36-46 (2014) Article DOI: 10.1016/j.ejmech.2014.05.015 BindingDB Entry DOI: 10.7270/Q21Z45ZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 4 (RAT) | BDBM50056415 (2-piperidinopropyl 4-amino-5-chloro-2-methoxybenzo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS-BIOCIS Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 4 receptor was determined in rat striatal membranes using [3H]GR-113808 as radioligand | J Med Chem 40: 608-21 (1997) Article DOI: 10.1021/jm960320m BindingDB Entry DOI: 10.7270/Q2T72J36 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 4 (Homo sapiens (Human)) | BDBM50056415 (2-piperidinopropyl 4-amino-5-chloro-2-methoxybenzo...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena Curated by ChEMBL | Assay Description Partial agonist activity at Rluc-tagged human 5HT4R expressed in human SH-SY5Y cells assessed as effect on serotonin-induced receptor/Gbeta1 coupling... | Eur J Med Chem 82: 36-46 (2014) Article DOI: 10.1016/j.ejmech.2014.05.015 BindingDB Entry DOI: 10.7270/Q21Z45ZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 4 (GUINEA PIG) | BDBM50056415 (2-piperidinopropyl 4-amino-5-chloro-2-methoxybenzo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a |
CNRS-BIOCIS Curated by ChEMBL | Assay Description 5-hydroxytryptamine 4 receptor agonist activity, concentration which gave 50% increase in the response to electrically-stimulated myenteric plexus an... | J Med Chem 40: 608-21 (1997) Article DOI: 10.1021/jm960320m BindingDB Entry DOI: 10.7270/Q2T72J36 | |||||||||||
More data for this Ligand-Target Pair |