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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 4' and Ligand = 'BDBM50456138'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 4


(Homo sapiens (Human))		BDBM50456138
PNG
(CHEMBL4208302)
Show SMILES CC(C)c1cn2cccc(C(=O)NCC3CCN(CC4CCOCC4)CC3)c2n1
Show InChI InChI=1S/C23H34N4O2/c1-17(2)21-16-27-9-3-4-20(22(27)25-21)23(28)24-14-18-5-10-26(11-6-18)15-19-7-12-29-13-8-19/h3-4,9,16-19H,5-8,10-15H2,1-2H3,(H,24,28)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 0.600n/an/an/an/a



Suven Life Sciences Limited

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human 5-HT4E receptor expressed in CHO cells assessed as induction of c-AMP accumulation after 4 hrs by luciferase re...

J Med Chem 61: 4993-5008 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00457
BindingDB Entry DOI: 10.7270/Q21R6T32
More data for this
Ligand-Target Pair