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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 4' and Ligand = 'BDBM50456152'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 4


(Homo sapiens (Human))		BDBM50456152
PNG
(CHEMBL4216003)
Show SMILES CC(C)c1cn2cccc(C(=O)NCC3CCN(CC(C)(C)O)CC3)c2n1
Show InChI InChI=1S/C21H32N4O2/c1-15(2)18-13-25-9-5-6-17(19(25)23-18)20(26)22-12-16-7-10-24(11-8-16)14-21(3,4)27/h5-6,9,13,15-16,27H,7-8,10-12,14H2,1-4H3,(H,22,26)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 0.700n/an/an/an/a



Suven Life Sciences Limited

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human 5-HT4E receptor expressed in CHO cells assessed as induction of c-AMP accumulation after 4 hrs by luciferase re...

J Med Chem 61: 4993-5008 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00457
BindingDB Entry DOI: 10.7270/Q21R6T32
More data for this
Ligand-Target Pair