Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 6' and Ligand = 'BDBM103947'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM103947 (CHEMBL2172190 | US8569318, 2.2(3)) Show SMILES CSc1nn2cc3CN(C)CCc3nc2c1S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C17H17FN4O2S2/c1-21-8-7-14-11(9-21)10-22-16(19-14)15(17(20-22)25-2)26(23,24)13-5-3-12(18)4-6-13/h3-6,10H,7-9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HE293 cells assessed as inhibition of serotonin-induced cAMP accumulation after 2...				Bioorg Med Chem Lett 22: 4273-80 (2012) Article DOI: 10.1016/j.bmcl.2012.05.036 BindingDB Entry DOI: 10.7270/Q2VH5PZ8
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM103947 (CHEMBL2172190 | US8569318, 2.2(3)) Show SMILES CSc1nn2cc3CN(C)CCc3nc2c1S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C17H17FN4O2S2/c1-21-8-7-14-11(9-21)10-22-16(19-14)15(17(20-22)25-2)26(23,24)13-5-3-12(18)4-6-13/h3-6,10H,7-9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Activity test of serotonin 5-HT6 receptor antagonists of the general formulas 1, 2 in the setting of competitive binding to serotonin 5-HT6 receptors...				US Patent US8569318 (2013) BindingDB Entry DOI: 10.7270/Q2JH3JT8
					More data for this Ligand-Target Pair