Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 6' and Ligand = 'BDBM328412'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM328412 (6-chloro-3-ethyl-1-((4-methoxy-3-(piperazin-1-yl)p...) Show SMILES CCc1cn(c2cc(Cl)ccc12)S(=O)(=O)c1ccc(OC)c(c1)N1CCNCC1 Show InChI InChI=1S/C21H24ClN3O3S/c1-3-15-14-25(19-12-16(22)4-6-18(15)19)29(26,27)17-5-7-21(28-2)20(13-17)24-10-8-23-9-11-24/h4-7,12-14,23H,3,8-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.450	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...				US Patent US9663498 (2017) BindingDB Entry DOI: 10.7270/Q22N54C8
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