Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 6' and Ligand = 'BDBM50217894'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217894 (1-(1-ethylpiperidin-3-yl)-3-[(3,5-dichlorophenyl)-...) Show SMILES CCN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cc(Cl)cc(Cl)c1 |w:6.8| Show InChI InChI=1S/C20H21Cl2N3O2S/c1-2-24-8-4-5-16(12-24)25-13-19(18-6-3-7-23-20(18)25)28(26,27)17-10-14(21)9-15(22)11-17/h3,6-7,9-11,13,16H,2,4-5,8,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Binding affinity to 5HT6 receptor				Eur J Med Chem 45: 3911-5 (2010) Article DOI: 10.1016/j.ejmech.2010.05.045 BindingDB Entry DOI: 10.7270/Q27945XK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217894 (1-(1-ethylpiperidin-3-yl)-3-[(3,5-dichlorophenyl)-...) Show SMILES CCN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cc(Cl)cc(Cl)c1 |w:6.8| Show InChI InChI=1S/C20H21Cl2N3O2S/c1-2-24-8-4-5-16(12-24)25-13-19(18-6-3-7-23-20(18)25)28(26,27)17-10-14(21)9-15(22)11-17/h3,6-7,9-11,13,16H,2,4-5,8,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217894 (1-(1-ethylpiperidin-3-yl)-3-[(3,5-dichlorophenyl)-...) Show SMILES CCN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cc(Cl)cc(Cl)c1 |w:6.8| Show InChI InChI=1S/C20H21Cl2N3O2S/c1-2-24-8-4-5-16(12-24)25-13-19(18-6-3-7-23-20(18)25)28(26,27)17-10-14(21)9-15(22)11-17/h3,6-7,9-11,13,16H,2,4-5,8,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	67	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at human 5HT6 expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassay				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair