Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 6' and Ligand = 'BDBM50217914'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217914 (3-(3-chloro-benzenesulfonyl)-1-(1-ethyl-pyrrolidin...) Show SMILES CCN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(Cl)c1 |w:5.7| Show InChI InChI=1S/C19H20ClN3O2S/c1-2-22-10-8-15(12-22)23-13-18(17-7-4-9-21-19(17)23)26(24,25)16-6-3-5-14(20)11-16/h3-7,9,11,13,15H,2,8,10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217914 (3-(3-chloro-benzenesulfonyl)-1-(1-ethyl-pyrrolidin...) Show SMILES CCN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(Cl)c1 |w:5.7| Show InChI InChI=1S/C19H20ClN3O2S/c1-2-22-10-8-15(12-22)23-13-18(17-7-4-9-21-19(17)23)26(24,25)16-6-3-5-14(20)11-16/h3-7,9,11,13,15H,2,8,10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Binding affinity to 5HT6 receptor				Eur J Med Chem 45: 3911-5 (2010) Article DOI: 10.1016/j.ejmech.2010.05.045 BindingDB Entry DOI: 10.7270/Q27945XK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217914 (3-(3-chloro-benzenesulfonyl)-1-(1-ethyl-pyrrolidin...) Show SMILES CCN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(Cl)c1 |w:5.7| Show InChI InChI=1S/C19H20ClN3O2S/c1-2-22-10-8-15(12-22)23-13-18(17-7-4-9-21-19(17)23)26(24,25)16-6-3-5-14(20)11-16/h3-7,9,11,13,15H,2,8,10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human 5HT6 expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassay				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair