Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 6' and Ligand = 'BDBM50217921'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217921 (3-[(3,5-dichlorophenyl)sulfonyl]-1-piperidin-3-yl-...) Show SMILES Clc1cc(Cl)cc(c1)S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12 |w:14.14| Show InChI InChI=1S/C18H17Cl2N3O2S/c19-12-7-13(20)9-15(8-12)26(24,25)17-11-23(14-3-1-5-21-10-14)18-16(17)4-2-6-22-18/h2,4,6-9,11,14,21H,1,3,5,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217921 (3-[(3,5-dichlorophenyl)sulfonyl]-1-piperidin-3-yl-...) Show SMILES Clc1cc(Cl)cc(c1)S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12 |w:14.14| Show InChI InChI=1S/C18H17Cl2N3O2S/c19-12-7-13(20)9-15(8-12)26(24,25)17-11-23(14-3-1-5-21-10-14)18-16(17)4-2-6-22-18/h2,4,6-9,11,14,21H,1,3,5,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Binding affinity to 5HT6 receptor				Eur J Med Chem 45: 3911-5 (2010) Article DOI: 10.1016/j.ejmech.2010.05.045 BindingDB Entry DOI: 10.7270/Q27945XK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217921 (3-[(3,5-dichlorophenyl)sulfonyl]-1-piperidin-3-yl-...) Show SMILES Clc1cc(Cl)cc(c1)S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12 |w:14.14| Show InChI InChI=1S/C18H17Cl2N3O2S/c19-12-7-13(20)9-15(8-12)26(24,25)17-11-23(14-3-1-5-21-10-14)18-16(17)4-2-6-22-18/h2,4,6-9,11,14,21H,1,3,5,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	297	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at human 5HT6 expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassay				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair