Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50277017 (4-(naphthalen-1-ylsulfonyl)-2-(piperazin-1-yl)benz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells | Bioorg Med Chem Lett 19: 1115-7 (2009) Article DOI: 10.1016/j.bmcl.2008.12.107 BindingDB Entry DOI: 10.7270/Q2X066WD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50277017 (4-(naphthalen-1-ylsulfonyl)-2-(piperazin-1-yl)benz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as blockage of 5HT-stimulated cAMP formation after 10 mins b... | Bioorg Med Chem Lett 19: 1115-7 (2009) Article DOI: 10.1016/j.bmcl.2008.12.107 BindingDB Entry DOI: 10.7270/Q2X066WD | |||||||||||
More data for this Ligand-Target Pair |