Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 6' and Ligand = 'BDBM50313140'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313140 (3-(3-fluorophenylsulfonyl)-1-(pyrrolidin-3-yl)-1H-...) Show SMILES Fc1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2ccccc12 Show InChI InChI=1S/C18H17FN2O2S/c19-13-4-3-5-15(10-13)24(22,23)18-12-21(14-8-9-20-11-14)17-7-2-1-6-16(17)18/h1-7,10,12,14,20H,8-9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313140 (3-(3-fluorophenylsulfonyl)-1-(pyrrolidin-3-yl)-1H-...) Show SMILES Fc1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2ccccc12 Show InChI InChI=1S/C18H17FN2O2S/c19-13-4-3-5-15(10-13)24(22,23)18-12-21(14-8-9-20-11-14)17-7-2-1-6-16(17)18/h1-7,10,12,14,20H,8-9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	68	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as effect on 5HT-induced intracellular cAMP level after 10 mins by ra...				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair