Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 6' and Ligand = 'BDBM50322102'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50322102 (3-(3-chlorophenylsulfonyl)-N-(pyridin-3-ylmethyl)t...) Show SMILES Clc1cccc(c1)S(=O)(=O)c1nnn2c3ccsc3c(NCc3cccnc3)nc12 Show InChI InChI=1S/C19H13ClN6O2S2/c20-13-4-1-5-14(9-13)30(27,28)19-18-23-17(22-11-12-3-2-7-21-10-12)16-15(6-8-29-16)26(18)25-24-19/h1-10H,11H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Binding affinity to human recombinant 5HT6 receptor expressed in HEK293 cells by radioligand displacement assay				Bioorg Med Chem 18: 5282-90 (2010) Article DOI: 10.1016/j.bmc.2010.05.051 BindingDB Entry DOI: 10.7270/Q2F190QT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50322102 (3-(3-chlorophenylsulfonyl)-N-(pyridin-3-ylmethyl)t...) Show SMILES Clc1cccc(c1)S(=O)(=O)c1nnn2c3ccsc3c(NCc3cccnc3)nc12 Show InChI InChI=1S/C19H13ClN6O2S2/c20-13-4-1-5-14(9-13)30(27,28)19-18-23-17(22-11-12-3-2-7-21-10-12)16-15(6-8-29-16)26(18)25-24-19/h1-10H,11H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31.7	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Binding affinity to human recombinant 5HT6 receptor expressed in HEK293 cells by radioligand displacement assay				Bioorg Med Chem 18: 5282-90 (2010) Article DOI: 10.1016/j.bmc.2010.05.051 BindingDB Entry DOI: 10.7270/Q2F190QT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50322102 (3-(3-chlorophenylsulfonyl)-N-(pyridin-3-ylmethyl)t...) Show SMILES Clc1cccc(c1)S(=O)(=O)c1nnn2c3ccsc3c(NCc3cccnc3)nc12 Show InChI InChI=1S/C19H13ClN6O2S2/c20-13-4-1-5-14(9-13)30(27,28)19-18-23-17(22-11-12-3-2-7-21-10-12)16-15(6-8-29-16)26(18)25-24-19/h1-10H,11H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP production				Bioorg Med Chem 18: 5282-90 (2010) Article DOI: 10.1016/j.bmc.2010.05.051 BindingDB Entry DOI: 10.7270/Q2F190QT
					More data for this Ligand-Target Pair