Found 4 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 7' and Ligand = 'BDBM50024206' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
5-hydroxytryptamine receptor 7
(Rattus norvegicus (rat)) | BDBM50024206
(3-[2-(dimethylamino)ethyl]-1H-indol-5-ol | 3-[2-(d...)Show InChI InChI=1S/C12H16N2O/c1-14(2)6-5-9-8-13-12-4-3-10(15)7-11(9)12/h3-4,7-8,13,15H,5-6H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| Purchase
CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 7.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
State University of Groningen
Curated by ChEMBL
| Assay Description
Binding affinity at rat 5-hydroxytryptamine 7 receptor. |
J Med Chem 46: 5365-74 (2003)
Article DOI: 10.1021/jm030826m
BindingDB Entry DOI: 10.7270/Q2K93B8V |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(GUINEA PIG) | BDBM50024206
(3-[2-(dimethylamino)ethyl]-1H-indol-5-ol | 3-[2-(d...)Show InChI InChI=1S/C12H16N2O/c1-14(2)6-5-9-8-13-12-4-3-10(15)7-11(9)12/h3-4,7-8,13,15H,5-6H2,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 19.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Syntex Discovery Research
Curated by PDSP Ki Database
| |
J Neurochem 63: 456-64 (1994)
Article DOI: 10.1046/j.1471-4159.1994.63020456.x
BindingDB Entry DOI: 10.7270/Q2N8788T |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(GUINEA PIG) | BDBM50024206
(3-[2-(dimethylamino)ethyl]-1H-indol-5-ol | 3-[2-(d...)Show InChI InChI=1S/C12H16N2O/c1-14(2)6-5-9-8-13-12-4-3-10(15)7-11(9)12/h3-4,7-8,13,15H,5-6H2,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 21.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Syntex Discovery Research
Curated by PDSP Ki Database
| |
Br J Pharmacol 115: 107-16 (1995)
Article DOI: 10.1111/j.1476-5381.1995.tb16327.x
BindingDB Entry DOI: 10.7270/Q2610XTR |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(GUINEA PIG) | BDBM50024206
(3-[2-(dimethylamino)ethyl]-1H-indol-5-ol | 3-[2-(d...)Show InChI InChI=1S/C12H16N2O/c1-14(2)6-5-9-8-13-12-4-3-10(15)7-11(9)12/h3-4,7-8,13,15H,5-6H2,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 95.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Syntex Discovery Research
Curated by PDSP Ki Database
| |
Br J Pharmacol 115: 107-16 (1995)
Article DOI: 10.1111/j.1476-5381.1995.tb16327.x
BindingDB Entry DOI: 10.7270/Q2610XTR |
More data for this
Ligand-Target Pair | |
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