Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 7' and Ligand = 'BDBM50403763'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50403763 (CHEMBL12908) Show SMILES COc1ccccc1N1CCN(CCCCCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 Show InChI InChI=1S/C27H33N3O3S/c1-33-25-14-5-4-12-23(25)29-20-18-28(19-21-29)16-6-2-3-7-17-30-24-13-8-10-22-11-9-15-26(27(22)24)34(30,31)32/h4-5,8-15H,2-3,6-7,16-21H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 7 receptor using [3H]-5-CT in rat hypothalamus membranes				Bioorg Med Chem Lett 10: 1097-100 (2000) BindingDB Entry DOI: 10.7270/Q2JS9RNJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50403763 (CHEMBL12908) Show SMILES COc1ccccc1N1CCN(CCCCCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 Show InChI InChI=1S/C27H33N3O3S/c1-33-25-14-5-4-12-23(25)29-20-18-28(19-21-29)16-6-2-3-7-17-30-24-13-8-10-22-11-9-15-26(27(22)24)34(30,31)32/h4-5,8-15H,2-3,6-7,16-21H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cracow University of Technology Curated by ChEMBL					Assay Description Binding affinity to 5HT7 (unknown origin)				Bioorg Med Chem 27: 3396-3407 (2019) Article DOI: 10.1016/j.bmc.2019.06.028 BindingDB Entry DOI: 10.7270/Q20K2D06
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50403763 (CHEMBL12908) Show SMILES COc1ccccc1N1CCN(CCCCCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 Show InChI InChI=1S/C27H33N3O3S/c1-33-25-14-5-4-12-23(25)29-20-18-28(19-21-29)16-6-2-3-7-17-30-24-13-8-10-22-11-9-15-26(27(22)24)34(30,31)32/h4-5,8-15H,2-3,6-7,16-21H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.				J Med Chem 46: 5638-50 (2003) Article DOI: 10.1021/jm030841r BindingDB Entry DOI: 10.7270/Q29W0J74
					More data for this Ligand-Target Pair