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Found 1 hit Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 7' and Ligand = 'BDBM50474453'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50474453
PNG
(CHEMBL356653)
Show SMILES O=C1N(CCCN2CCN(CC2)c2ccccc2)c2cccc3cccc1c23
Show InChI InChI=1S/C24H25N3O/c28-24-21-11-4-7-19-8-5-12-22(23(19)21)27(24)14-6-13-25-15-17-26(18-16-25)20-9-2-1-3-10-20/h1-5,7-12H,6,13-18H2
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PC cid
PC sid
UniChem
Article
PubMed
<1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair