Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '5-lipoxygenase' and Ligand = 'BDBM50043373'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-lipoxygenase (Bos taurus)	BDBM50043373 (10-[2-(3,4-Dihydroxy-phenyl)-acetyl]-1,8-dihydroxy...) Show SMILES Oc1ccc(CC(=O)C2c3cccc(O)c3C(=O)c3c(O)cccc23)cc1O Show InChI InChI=1S/C22H16O6/c23-14-8-7-11(9-17(14)26)10-18(27)19-12-3-1-5-15(24)20(12)22(28)21-13(19)4-2-6-16(21)25/h1-9,19,23-26H,10H2	PDB MMDB Reactome pathway UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universität Regensburg Curated by ChEMBL					Assay Description Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomes				J Med Chem 36: 4099-107 (1994) BindingDB Entry DOI: 10.7270/Q2G44PC2
					More data for this Ligand-Target Pair
5-lipoxygenase (Bos taurus)	BDBM50043373 (10-[2-(3,4-Dihydroxy-phenyl)-acetyl]-1,8-dihydroxy...) Show SMILES Oc1ccc(CC(=O)C2c3cccc(O)c3C(=O)c3c(O)cccc23)cc1O Show InChI InChI=1S/C22H16O6/c23-14-8-7-11(9-17(14)26)10-18(27)19-12-3-1-5-15(24)20(12)22(28)21-13(19)4-2-6-16(21)25/h1-9,19,23-26H,10H2	PDB MMDB Reactome pathway UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universität Regensburg Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).				J Med Chem 36: 4099-107 (1994) BindingDB Entry DOI: 10.7270/Q2G44PC2
					More data for this Ligand-Target Pair