BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = '6,7-dimethyl-8-ribityllumazine synthase' and Ligand = 'BDBM50316581'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
6,7-dimethyl-8-ribityllumazine synthase (Mycobacterium tuberculosis)	BDBM50316581 (5-(2-Oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamido)...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-substrate complex state after 30 mins by fluorescence assay				Bioorg Med Chem 18: 3518-34 (2010) Article DOI: 10.1016/j.bmc.2010.03.072 BindingDB Entry DOI: 10.7270/Q29P31S5
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
6,7-dimethyl-8-ribityllumazine synthase (Mycobacterium tuberculosis)	BDBM50316581 (5-(2-Oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamido)...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.63E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-substrate-inhibitor complex state after 30 mins by fluorescence assa...				Bioorg Med Chem 18: 3518-34 (2010) Article DOI: 10.1016/j.bmc.2010.03.072 BindingDB Entry DOI: 10.7270/Q29P31S5
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair